A corneal infection can often result from an eye injury, trauma or other forms of eye damage. Contact lens wearers are susceptible, as the lens rubs on the cornea which could lead to slight damage to the epithelium, allowing bacteria to enter. Proper hand hygiene before handling contacts can reduce the risk of bacteria infecting the eye.
Melting ulcers can be caused by Pseudomonas bacteria that break down the stroma or supportive tissue of the cornea. The breakdown of these fibers can also lead to corneal perforation (a hole in the cornea).